I read this very interesting article about tips for designing for localised interfaces and found that all of these principles completely apply to designing for a website for a SiteCM Content Managed website.
For those that are not familiar with it, website localization at its most basic is translating and adapting web sites to be used in other countries. ideaLEVER's eCommerce platform CommerceCM was built for multi-lingual eCommerce so this is the sort of thing we deal with a lot. The basic issues though apply to any site built with a CMS where you as the designer can't control what the end user will do with your pretty design.
The 10 tips in this article will help all web designers working with a CMS to make sure that your design has enough flexibility to deal with whatever your users throw at you.
http://www.creativebloq.com/design/10-tips-designing-localised-interfaces-3132922
Hope this helps someone!